No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Ready to participate?
Review the details below, then apply to join this clinical trial.
At a Glance
Age
45 – 89
Sex
Any
Study type
Interventional
Purpose
Prevention
Participants needed
64 (estimated)
Sponsor
Georgia State University · Other
Who this trial is looking for
This trial is looking for people with multiple sclerosis who are at least 45 years old. Participants will learn to improve their motor skills through training that involves balancing on slips and trips.
Are You a Good Fit for This Trial?
You may be able to join if
I have been diagnosed with multiple sclerosis.
I am at least 45 years old.
I can walk independently at least 25 feet.
I can stand independently for at least 30 seconds.
My Patient Determined Disability Steps score is between 0 and 4.
I am not pregnant.
I have a Montreal Cognitive Assessment score of 23 or higher.
You may not be able to join if
I have previous experience with perturbation training.
I have a T-score of less than -2.5 from a DXA scan.
I have coexisting psychiatric disorders or other neurological conditions.
I have severe medical illnesses or cardiovascular diseases.
I have had a relapse in the past 8 weeks.
Summarized in plain language from this trial's official eligibility criteria.
The full criteria are further down this page — only the research team can
confirm whether you qualify.
Think this trial could be right for you?
Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.
The primary purpose of this interventional study is to examine the overall motor learning capacity from exposure to repeated perturbations among ambulatory people with multiple sclerosis (MS). This project will advance our understanding of learning new motor skills from exposure to external perturbations. If it is proven that people with MS can learn motor skills from perturbation training, the fi…
The primary purpose of this interventional study is to examine the overall motor learning capacity from exposure to repeated perturbations among ambulatory people with multiple sclerosis (MS). This project will advance our understanding of learning new motor skills from exposure to external perturbations. If it is proven that people with MS can learn motor skills from perturbation training, the findings from this study will pave a theoretical foundation for applying perturbation training as a promising fall prevention intervention for people with MS.
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
1. Clinically confirmed multiple sclerosis
2. At least 45 years old
3. Able to walk independently at least 25 feet
4. Able to stand independently for at least 30 seconds
5. Patient Determined Disability Steps score between 0 and 4
6. Free from pregnancy
7. Montreal Cognitive Ass…
Inclusion Criteria:
1. Clinically confirmed multiple sclerosis
2. At least 45 years old
3. Able to walk independently at least 25 feet
4. Able to stand independently for at least 30 seconds
5. Patient Determined Disability Steps score between 0 and 4
6. Free from pregnancy
7. Montreal Cognitive Assessment score of 23 or higher
Exclusion Criteria:
1. Previous experience with perturbation training
2. T-score from the dual x-ray absorptiometry (DXA) scan of less than -2.5
3. Coexisting psychiatric disorders or other neurological conditions, severe medical illness, or cardiovascular diseases
4. Participants have had a relapse in the past 8 weeks
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