SGLT2 Inhibitors for Adult Congenital Heart Disease

Adult Congenital Heart Disease International EValuation of the Effectiveness of SGLT2i Registry

Recruiting Observational Study
Adult Congenital Heart Disease Congenital Heart Disease Systemic Right Ventricle Transposition of the Great Arteries Congenitally Corrected Transposition of the Great Arteries Fontan Single Ventricle Tetralogy of Fallot (TOF)
No Placebo Group Every participant receives an active treatment — no one gets a placebo. No Study Drug Researchers observe your health over time — no experimental treatment is given.
Ready to participate?

Review the details below, then apply to join this clinical trial.

At a Glance
Age
18 and older
Sex
Any
Study type
Observational
Participants needed
400 (estimated)
Sponsor
Leiden University Medical Center · Other
Who this trial is looking for

This trial is looking for adults with congenital heart defects who have started treatment with SGLT2 inhibitors. Participation involves allowing researchers to collect data on how these drugs affect heart health and safety.

Are You a Good Fit for This Trial?

You may be able to join if

  • I have a congenital heart defect.
  • I am 18 years or older.
  • I have started treatment with an SGLT2 inhibitor.

You may not be able to join if

  • I did not give consent for data collection.

Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.

Think this trial could be right for you?

Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.

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About This Trial

This real-world, international registry aims to evaluate the current experience with sodium-glucose cotransporter 2 inhibitors (SGLT2i) in adult congenital heart disease (ACHD) patients by investigating the prescription patterns, safety, tolerability, and potential beneficial effects on heart failure-related outcomes.

Trial Locations
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Eligibility Criteria
Inclusion Criteria: * Congenital heart defect. * Age ≥ 18 years. * Initiated on treatment with an SGLT2i. Exclusion Criteria: \- No consent for data collection.
Contacts

Ralph M.L. Neijenhuis, MD

+31 71 5262020

r.m.l.neijenhuis@lumc.nl

CONTACT

Björn N. Westdorp, MD

+31 71 5262020

b.n.westdorp@lumc.nl

CONTACT