LE + CC vs. LE for Ovulation Induction
Recruiting
N/A
Interventional Study
Letrozole
Clomiphene Citrate
Ovulation Disorder
Ovulation Induction
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
At a Glance
- Age
- 18 – 40
- Sex
- Female
- Study type
- Interventional
- Purpose
- Treatment
- Participants needed
- 600 (estimated)
- Sponsor
- Mỹ Đức Hospital · Other
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About This Trial
This randomized controlled trial (RCT) aims to evaluate whether, in infertile women with WHO II/IV ovulatory disorders, a combination of letrozole (LE) and clomiphene citrate (CC) compared to LE alone, result in higher live birth rates.
The study is designed as an open-label, multicenter RCT across six fertility clinics in Vietnam. Participants will be randomized into two groups: (1) LE + CC , (2…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Women 18-40 years of age
* Having ovulation disorder (length of cycle \< 21 or \> 35 days or having \< 8 cycles per year)
* FSH ≥5 IU/L and ≤25 IU/L, or LH ≥5 IU/L and AMH ≥1.2 ng/mL
* Progressive motility (PR) ≥ 32% OR total progressive motility sperm count \> 5 million; and …
Contacts