LE + CC vs. LE for Ovulation Induction

Recruiting N/A Interventional Study
Letrozole Clomiphene Citrate Ovulation Disorder Ovulation Induction
No Placebo Group Every participant receives an active treatment — no one gets a placebo.
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At a Glance
Age
18 – 40
Sex
Female
Study type
Interventional
Purpose
Treatment
Participants needed
600 (estimated)
Sponsor
Mỹ Đức Hospital · Other
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About This Trial
This randomized controlled trial (RCT) aims to evaluate whether, in infertile women with WHO II/IV ovulatory disorders, a combination of letrozole (LE) and clomiphene citrate (CC) compared to LE alone, result in higher live birth rates. The study is designed as an open-label, multicenter RCT across six fertility clinics in Vietnam. Participants will be randomized into two groups: (1) LE + CC , (2…
Trial Locations
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Eligibility Criteria
Inclusion Criteria: * Women 18-40 years of age * Having ovulation disorder (length of cycle \< 21 or \> 35 days or having \< 8 cycles per year) * FSH ≥5 IU/L and ≤25 IU/L, or LH ≥5 IU/L and AMH ≥1.2 ng/mL * Progressive motility (PR) ≥ 32% OR total progressive motility sperm count \> 5 million; and …
Contacts

Van TT Tran, MD

+84353345020

bsvan.ttt@myduchospital.vn

CONTACT

Vinh Q Dang, MSc,MD

vinh.dang@monash.edu

CONTACT