Effect of Dynamic Arterial Elastance and Assisted Fluid Management Software Guided Resuscitation in Septic Shock: Pilot Study

Recruiting N/A Interventional Study
Critical Illness Fluid Over-load Dynamic Arterial Elastance Septic Shock
No Placebo Group Every participant receives an active treatment — no one gets a placebo.
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At a Glance
Age
18 and older
Sex
Any
Study type
Interventional
Purpose
Supportive Care
Participants needed
60 (estimated)
Sponsor
Mahidol University · Other
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About This Trial

To investigate the benefit of using the AFM and Eadyn-guided fluid and vasopressor therapy in septic shock resuscitation for mechanically ventilated patients compared with the standard of care. The investigators hypothesize that using the AFM and Eadyn-guided fluid/vasopressor titration in septic shock patients who underwent mechanical ventilation might reduce the time to shock reversal.

Trial Locations
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Eligibility Criteria
Inclusion Criteria: * All Thai consecutive patients older than 18 years with a diagnosis of sepsis or septic shock in medical ICU, defined by clinically suspected or confirmed infection and MAP \<65 mmHg according to the criteria of the Surviving Sepsis Campaign 2021(11)with onset of shock in less …
Contacts

Ranistha Ratanarat, MD

+66 2419 7767

ranittha@gmail.com

CONTACT

Nuwara Pornawalai, MD

+66 2419 7767

nuwara.por@gmail.com

CONTACT