Genicular Artery Embolization for Knee Osteoarthritis

Evaluating Changes in Synovial Fluid Before and After GAE for Knee Osteoarthritis

Recruiting N/A Interventional Study
Knee Osteoarthritis
No Placebo Group Every participant receives an active treatment — no one gets a placebo.
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Review the details below, then apply to join this clinical trial.

At a Glance
Age
18 and older
Sex
Any
Study type
Interventional
Purpose
Treatment
Participants needed
46 (estimated)
Sponsor
University of Colorado, Denver · Other
Who this trial is looking for

This trial is looking for adults with knee osteoarthritis who are in moderate to severe pain and are considering a specific procedure called genicular artery embolization (GAE). Participants will have MRIs and answer some questions before and after the procedure to see how it helps their condition.

Are You a Good Fit for This Trial?
Rules you out Active knee joint infectionAcute knee injuryPrior knee replacementRenal insufficiency

You may be able to join if

  • I am 18 years or older.
  • I plan to have genicular artery embolization for my knee osteoarthritis.
  • I have been diagnosed with knee osteoarthritis in the last 6 months.
  • I have had persistent moderate to severe knee pain for at least 6 months.
  • My pain has not improved with usual treatments.
  • My BMI is less than 35.
  • I am willing to follow study procedures.

You may not be able to join if

  • I have a serious bleeding disorder.
  • I take blood thinner medications that can't be paused for the procedure.
  • I am allergic to certain contrast agents and cannot take steroids beforehand.
  • I have an active infection in my knee joint.
  • I have had surgery due to a recent knee injury.
  • I have had a knee replacement in the past.
  • I had a steroid injection in my knee within the last 2 months.
  • I have a serious medical condition that affects my life expectancy.

Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.

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About This Trial
The goal of this clinical trial is to learn if genicular artery embolization (GAE) can improve knee pain and decrease inflammation in adults with knee osteoarthritis. The main question it aims to answer is: \- Does the GAE procedure improve knee pain and decrease inflammation? Researchers will compare synovial fluid samples taken from the knee before and after the procedure. Participants will: …
Trial Locations
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Eligibility Criteria
Inclusion Criteria: * Age ≥ 18 years * Planned to undergo genicular artery embolization to treat knee osteoarthritis. * Osteoarthritis on knee radiograph (Kellgren-Lawrence score 1-3) within the last 6 months * Persistent moderate to severe knee pain (visual analog scale \[VAS\] \>3) for at least 6…
Contacts

Shireen Shikak, BS

720.848.6618

shireen.shikak@cuanschutz.edu

CONTACT

Tricia Luna, MS, RN

720.848.6610

patricia.luna@cuanschutz.edu

CONTACT