Oxalate and Citrate in Humans - Response to Citrate

Recruiting N/A Interventional Study
Kidney Stone Healthy
No Placebo Group Every participant receives an active treatment — no one gets a placebo. Healthy Volunteers Welcome You do not need to have the condition being studied to take part.
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At a Glance
Age
18 – 70
Sex
Any
Study type
Interventional
Purpose
Prevention
Participants needed
24 (estimated)
Sponsor
University of Chicago · Other
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About This Trial

This is a single-center study that aims to learn more about how two compounds found in food, oxalate and citrate, interact in the body and may influence a person's chances of forming kidney stones. The study will examine changes in urinary oxalate and citrate levels after participants consume potassium citrate.

Trial Locations
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Eligibility Criteria
Inclusion Criteria: Stone formers (SF): * Age 18-70 * History of at least one calcium-based kidney stone Non-stone formers (NSF): * Age 18-70 * No history of kidney stone * 24-hour urine oxalate within laboratory normal range (\<50 mg/day) Exclusion Criteria: History of primarily uric acid, cy…
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