Glumetinib and Docetaxel for Advanced Gastric Cancer

Safety and Efficacy of Glumetinib Combined With Docetaxel for Injection (Albumin-bound) in Patients With Advanced Gastric Cancer/Gastroesophageal Junction Adenocarcinoma and Other Solid Tumors

Recruiting Phase 2 Interventional Study
Advanced Gastric Cancer/Gastroesophageal Junction Adenocarcinoma and Other Solid Tumors
No Placebo Group Every participant receives an active treatment — no one gets a placebo. Prior Safety Data This treatment has already been tested in at least one earlier human trial.
Ready to participate?

Review the details below, then apply to join this clinical trial.

At a Glance
Age
18 and older
Sex
Any
Trial phase
Phase 2
Study type
Interventional
Purpose
Treatment
Participants needed
350 (estimated)
Sponsor
CSPC ZhongQi Pharmaceutical Technology Co., Ltd. · Industry
Who this trial is looking for

This trial is looking for adults with advanced solid tumors. Participants will receive a combination treatment and will be monitored for safety and effectiveness.

Are You a Good Fit for This Trial?

You may be able to join if

  • I am at least 18 years old.
  • I have advanced solid tumors.
  • I understand and can sign the consent form.
  • I have measurable or evaluable lesions.
  • I have a Her-2 status that is known or has been determined.
  • I have a good performance status score of 0 or 1.
  • My expected survival time is at least 3 months.
  • My major organ and bone marrow function meets the study criteria.

You may not be able to join if

  • I have had prior treatment with targeted MET drugs.
  • I have previous treatment that included docetaxel.
  • I have meningeal metastases or symptomatic brain metastases.
  • I am hypersensitive to any of the study drugs.
  • I have not recovered from previous treatment side effects to a grade of 1 or less.
  • I have severe uncontrolled health issues.
  • I am pregnant or breastfeeding.
  • I do not plan to use effective contraception if applicable.

Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.

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About This Trial

The trial consists of Stage 1 (including dose escalation and dose expansion) and Stage 2 (proof-of-concept study). Among them, Stage 2 adopts a randomized, controlled, open-label, and multicenter design.

Trial Locations
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Eligibility Criteria
Inclusion Criteria: * 1\. Patients who are able to understand and voluntarily sign the written ICF; * 2\. Male or female patients aged ≥ 18 years (inclusive); * 3\. Patients with advanced solid tumors diagnosed by pathology or cytology; * 4\. Patients with a past medical history showing either nega…
Contacts

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86-0311-69085587

ctr-contact@cspc.cn

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