No Study Drug
Researchers observe your health over time — no experimental treatment is given.
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At a Glance
Age
18 – 75
Sex
Any
Study type
Observational
Participants needed
60 (estimated)
Sponsor
University of Chicago · Other
Who this trial is looking for
This trial is looking for adults with cirrhosis who are being evaluated for a liver transplant. Participants will wear a device to monitor their glucose levels and undergo tests before and after the transplant.
Are You a Good Fit for This Trial?
You may be able to join if
I have been diagnosed with cirrhosis.
I am over 18 years old.
I can understand and sign a consent form.
You may not be able to join if
I cannot give consent.
I have a device that cannot be removed or turned off.
I am pregnant.
I am currently incarcerated.
I was diagnosed with type 2 diabetes more than 5 years ago.
Summarized in plain language from this trial's official eligibility criteria.
The full criteria are further down this page — only the research team can
confirm whether you qualify.
Think this trial could be right for you?
Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.
The goal of this observational study is to establish risk factors for post-transplant in adult individuals with cirrhosis without diabetes undergoing liver transplant evaluation.
The question being addressed is: can laboratory work, anthropometric tests, functional tests, imaging, and advanced measurements such as wrist actigraphy, continuous glucose monitoring, or oral glucose tolerance testing …
The goal of this observational study is to establish risk factors for post-transplant in adult individuals with cirrhosis without diabetes undergoing liver transplant evaluation.
The question being addressed is: can laboratory work, anthropometric tests, functional tests, imaging, and advanced measurements such as wrist actigraphy, continuous glucose monitoring, or oral glucose tolerance testing predict the development of diabetes after liver transplant?
Participants will be asked to periodically participate in wearing a continuous glucose monitor and wrist actigraph and obtain an oral glucose tolerance test both before and after liver transplant.
Trial Locations
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Status
Eligibility Criteria
Inclusion Criteria:
* Patients presenting to liver transplant clinic with a diagnosis of cirrhosis.
* Age \>18 yrs.
* Ability to understand and sign written consent form, or have a legally-authorized representative or proxy who can be approached for consent
Exclusion Criteria:
* Patients without …
Inclusion Criteria:
* Patients presenting to liver transplant clinic with a diagnosis of cirrhosis.
* Age \>18 yrs.
* Ability to understand and sign written consent form, or have a legally-authorized representative or proxy who can be approached for consent
Exclusion Criteria:
* Patients without consent
* Patients with implantable cardioverter defibrillator devices or automated implantable cardioverter defibrillator devices will be excluded from the bio-electrical impedance analysis portion of the measurements.
* Patients with unremovable electrical medical devices or devices that cannot turn off will be excluded from the bio-electrical impedance analysis measurements
* Pregnant patients
* Incarcerated patients
* Patients with a history of type 2 diabetes mellitus diagnosed \> 5 years ago will be excluded from the Oral Glucose Tolerance Test portion of the study
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