SAR442970 for Moderate to Severe Crohn's Disease

A Study to Investigate Efficacy and Safety of Brivekimig in Participants With Crohn's Disease

Recruiting Phase 2 Interventional Study
Crohn's Disease
Prior Safety Data This treatment has already been tested in at least one earlier human trial.
Ready to participate?

Review the details below, then apply to join this clinical trial.

At a Glance
Age
18 – 75
Sex
Any
Trial phase
Phase 2
Study type
Interventional
Purpose
Treatment
Participants needed
99 (estimated)
Sponsor
Sanofi · Industry
Who this trial is looking for

This trial is looking for people with moderate to severe Crohn's disease who have not responded well to previous treatments. Participants will take different doses of the study drug or a placebo over a period of up to 158 weeks.

Are You a Good Fit for This Trial?

You may be able to join if

  • I have been diagnosed with Crohn's disease for at least 3 months.
  • I have moderate to severe Crohn's disease.
  • I have tried standard treatments but didn’t respond well to them.
  • I am on stable doses of standard treatments.
  • I will use contraception as required.

You may not be able to join if

  • I have active ulcerative colitis or other serious bowel issues.
  • I have Crohn's disease only in certain areas like the stomach or perianal region.
  • I need bowel surgery while in the study.
  • I have had bowel surgery in the last 3 months.
  • I have 3 or more bowel resections in my history.
  • I have a condition that could affect drug absorption.

Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.

Think this trial could be right for you?

Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.

Check Your Eligibility
About This Trial
This is a phase 2, randomized, double-blind, 3-arm study for the treatment of Crohn's disease. The primary objective of this study is to assess the efficacy of different doses of SAR442970 compared with placebo in participants with moderate to severe Crohn's disease. The total study duration is up to 168 weeks, with a treatment period of up to 158 weeks including an open-label (OL) long-term exten…
Trial Locations
Loading…

Loading trial locations…

Eligibility Criteria
Inclusion Criteria: * Diagnosis of Crohn's Disease (CD) for at least 3 months prior to screening * Confirmed diagnosis of moderate-to-severe CD * History of prior exposure to standard treatment and having inadequate response to, loss of response to or intolerance to standard therapy with any of the…
Contacts

Trial Transparency email recommended (Toll free for US & Canada)

800-633-1610

contact-us@sanofi.com

CONTACT