Deep Brain Stimulation Study for Parkinson's Disease
Cognitive Decline Following Deep Brain Stimulation: A DBS-fMRI Study
Recruiting
Observational Study
Deep Brain Stimulation
Parkinson Disease
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
At a Glance
- Age
- 18 and older
- Sex
- Any
- Study type
- Observational
- Participants needed
- 55 (estimated)
- Sponsor
- Medical University of South Carolina · Other
Who this trial is looking for
This trial is looking for people with Parkinson's disease who have had brain stimulation surgery. Participants will have two visits to take part in assessments and brain scans to understand the effects of the treatment on thinking and memory.
Are You a Good Fit for This Trial?
You may be able to join if
- I am over 18 years old
- I have been diagnosed with Parkinson's disease
- I have had a neurological evaluation at MUSC's movement disorder center
- I have undergone deep brain stimulation surgery
You may not be able to join if
- I have uncorrected vision or hearing problems
- I am pregnant or plan to become pregnant during the study
- I have a history of other neurological diseases
- I have claustrophobia or can't lie flat for MRI scans
- I have COPD and need oxygen support
- I have metal implants that are not compatible with MRI
Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.
Think this trial could be right for you?
Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.
Check Your Eligibility
About This Trial
The objective of this research study is to understand how Deep Brain Stimulation (DBS) targeting the subthalamic nucleus (STN) affects cognitive networks in the brain, potentially leading to cognitive decline in patients with Parkinson's Disease (PD). A total of 55 participants with PD who have undergone DBS surgery will be recruited from MUSC's Clinical DBS Program. Participants will attend two p…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Subjects above 18 years of age
* Individuals with a PD diagnosis as defined by the UK Brain Bank diagnostic criteria for Parkinson's disease (58) which have undergone a neurological and neuropsychological evaluation at MUSCs movement disorder center, and were selected to under…
Contacts