Optimizing Perioperative Analgesia to Lower Pain Following Cleft Palate Surgery

Recruiting Phase 4 Interventional Study
Cleft Palate Pain Postoperative Care Perioperative Care Children
No Placebo Group Every participant receives an active treatment — no one gets a placebo. Prior Safety Data This treatment has already been tested in at least one earlier human trial.
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At a Glance
Age
6 Months – 4
Sex
Any
Trial phase
Phase 4
Study type
Interventional
Purpose
Treatment
Participants needed
60 (estimated)
Sponsor
Duke University · Other
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About This Trial

The purpose of this study is to compare the use of short acting opioids (fentanyl/hydromorphone) with long acting opioids (methadone) for pain control following cleft palate surgery in infants and young children.

Trial Locations
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Eligibility Criteria
Inclusion Criteria: * Age 6 months to 4 years of age * Primary cleft palate repair * Signed informed consent by parent or legal guardian Exclusion Criteria: * History of chronic kidney or liver disease * Planned admission to the Pediatric Intensive Care Unit (PICU) * Additional procedures under g…
Contacts

Lisa M. Einhorn, M.D.

919 970 2805

lisa.einhorn@duke.edu

CONTACT