Evaluation of Fentanyl Transdermal Patch Absorption in Hemodynamically Unstable ICU Patients.

Recruiting Observational Study
Pain Management Critical Illness
No Placebo Group Every participant receives an active treatment — no one gets a placebo. No Study Drug Researchers observe your health over time — no experimental treatment is given.
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At a Glance
Age
18 – 70
Sex
Any
Study type
Observational
Participants needed
40 (estimated)
Sponsor
Tel-Aviv Sourasky Medical Center · Government
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About This Trial
This study investigates how well fentanyl is absorbed through the skin when delivered via a transdermal patch in critically ill surgical ICU patients. It compares hemodynamically stable patients with unstable patients who require vasopressors to maintain adequate blood pressure. Fentanyl blood levels will be measured over time to assess whether absorption is impaired in unstable patients. The goal…
Trial Locations
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Eligibility Criteria
Inclusion Criteria: * Adults aged 18-70 years. * Male or female patients. * Admitted to the surgical intensive care unit (ICU). * Indications for pain management using fentanyl. Exclusion Criteria: * No clinical indication for fentanyl analgesia (e.g., pain well controlled with non-opioid medicat…
Contacts

Avner Leshem, MD-PhD

+972-3-6973255

avnerle@tlvmc.gov.il

CONTACT