Predicting Psychotic Relapse Using Speech-Based Early Detection
Recruiting
Observational Study
Psychosis
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
Ready to participate?
Review the details below, then apply to join this clinical trial.
At a Glance
Age
16 and older
Sex
Any
Study type
Observational
Participants needed
250 (estimated)
Sponsor
Douglas Mental Health University Institute · Other
Who this trial is looking for
This trial is looking for people aged 16 and older who have been diagnosed with a psychotic disorder like schizophrenia. Participants will be involved in a research program that uses speech to help predict relapses in their condition.
Are You a Good Fit for This Trial?
You may be able to join if
I am 16 years or older
I have been diagnosed with a psychotic disorder
I speak English or French
I am currently receiving treatment through an Early Psychosis Intervention program
You may not be able to join if
I have a severe speech or language disorder
I have a non-psychotic disorder as my main diagnosis
I cannot give consent or take part in assessments
Summarized in plain language from this trial's official eligibility criteria.
The full criteria are further down this page — only the research team can
confirm whether you qualify.
Think this trial could be right for you?
Answer a few quick questions to see if you may meet the eligibility requirements.
Psychotic disorders, including schizophrenia and affective psychosis, are severe mental health conditions marked by recurrent episodes that contribute to long-term disability. Relapses, characterized by the re-emergence of psychotic symptoms after remission, are a critical factor in the progression of these disorders, increasing risks such as suicide, cognitive impairment, and unemployment. This s…
Psychotic disorders, including schizophrenia and affective psychosis, are severe mental health conditions marked by recurrent episodes that contribute to long-term disability. Relapses, characterized by the re-emergence of psychotic symptoms after remission, are a critical factor in the progression of these disorders, increasing risks such as suicide, cognitive impairment, and unemployment. This study aims to develop a novel, speech-based digital model to predict relapses in individuals with psychosis. Building on previous research into language abnormalities in schizophrenia, the study will employ a longitudinal design across Early Psychosis Intervention (EPI) clinics in Ontario and Quebec to advance relapse prediction
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Age must be 16 years and older
* Diagnosis must meet DSM-5 criteria for psychotic disorders, including schizophrenia, schizoaffective disorder, or related conditions
* Fluency in English or French
* Must be currently receiving treatment through an EPI program
Exclusion Criter…
Inclusion Criteria:
* Age must be 16 years and older
* Diagnosis must meet DSM-5 criteria for psychotic disorders, including schizophrenia, schizoaffective disorder, or related conditions
* Fluency in English or French
* Must be currently receiving treatment through an EPI program
Exclusion Criteria:
* Severe comorbid speech or language disorders (e.g., aphasia)
* Primary diagnosis of non-psychotic disorders
* Inability to provide consent or complete assessments
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