ANI-Guided Anesthetic Desflurane Consumption
Recruiting
N/A
Interventional Study
Postoperative Pain
General Anesthesia
Laparoscopic Cholecystectomy
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
At a Glance
- Age
- 19 – 65
- Sex
- Any
- Study type
- Interventional
- Purpose
- Treatment
- Participants needed
- 125 (estimated)
- Sponsor
- Wonkwang University Hospital · Other
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About This Trial
General anesthesia requires precise titration of inhaled anesthetics like desflurane and opioids like remifentanil to balance sedation, analgesia, and hemodynamic stability. The Analgesia/Nociception Index (ANI), derived from heart rate variability (HRV), quantifies parasympathetic tone to assess nociception-antinociception balance on a 0-100 scale, with lower values indicating nociceptive stress.…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* aged 19-65 years, American Society of Anesthesiologists (ASA) physical status I-II, scheduled for elective laparoscopic cholecystectomy under general anesthesia.
Exclusion Criteria:
* chronic pain, preoperative opioid use, cardiac arrhythmias, autonomic dysfunction, or contr…
Contacts