Neural Correlates and Behavioral Impact of Withdrawal-induced Hyperalgesia Among People Who Smoke With and Without Chronic Pain
Recruiting
N/A
Interventional Study
Tobacco Use
Chronic Pain
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
At a Glance
- Age
- 21 – 65
- Sex
- Any
- Study type
- Interventional
- Purpose
- Basic Science
- Participants needed
- 132 (estimated)
- Sponsor
- Duke University · Other
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About This Trial
Individuals with chronic pain are more likely to smoke cigarettes and have more difficulty quitting smoking than the general population, in part because withdrawal from smoking can lead to temporary increases in pain. This research will examine how smoking withdrawal changes the way the brain processes pain, and whether these withdrawal-related changes interfere with the ability to stop smoking. T…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
1. History of chronic non-cancer low back pain with duration ≥ 6 months OR no history of chronic pain;
2. age 21-65;
3. smoking of at least 10 cig/day for \> 2 years;
4. have an iPhone or Android smartphone capable of running the EMA software
Exclusion Criteria:
1. pain compla…
Contacts