The Kidney's Response to Exercise in Heat, and the Impact of Vitamin B3 on This Response
Recruiting
Early Phase 1
Interventional Study
Heat Strain
Healthy Volunteer Study
Kidney Dysfunction
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
At a Glance
- Age
- 18 – 45
- Sex
- Any
- Trial phase
- Early Phase 1
- Study type
- Interventional
- Purpose
- Basic Science
- Participants needed
- 28 (estimated)
- Sponsor
- Beth Israel Deaconess Medical Center · Other
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About This Trial
The goal of this clinical trial is to learn about the processes occurring in the kidneys while under heat stress in healthy volunteers. The main questions it aims to answer are:
* How do the chemicals produced by the body change under conditions of higher versus lower heat stress?
* What role does a specific area of the body's metabolism, known as NAD+ metabolism, play in the body's response to h…
Trial Locations
Sorted by distance from Kansas
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Eligibility Criteria
Inclusion Criteria:
* Healthy volunteer
* Any race
* Estimated glomerular filtration rate greater than 90 ml/min/1.73m2
* Urine albumin/creatinine ratio less than 30mg/g
* Nonsmoker
* No regular dietary supplements, particularly vitamin B3
* Physically fit, defined as having a VO2 max of between 35…
Contacts