No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
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At a Glance
Age
18 and older
Sex
Any
Study type
Interventional
Purpose
Treatment
Participants needed
60 (estimated)
Sponsor
Northwestern University · Other
Who this trial is looking for
This trial is looking for African American adults with high blood pressure and depression. Participants will join an 8-week mindfulness program to help manage stress and improve their symptoms.
Are You a Good Fit for This Trial?
You may be able to join if
I am at least 18 years old
I spend time in the South Side of Chicago
I have been diagnosed with high blood pressure
I have elevated depressive symptoms
I am not taking antidepressant medication or have been stable on it for at least 6 months
You may not be able to join if
I am under 18 years old
I have a severe mental illness
I currently have thoughts of suicide or have attempted suicide in the past 6 months
I cannot provide informed consent or complete study activities in English
Summarized in plain language from this trial's official eligibility criteria.
The full criteria are further down this page — only the research team can
confirm whether you qualify.
Think this trial could be right for you?
Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.
The goal of this clinical trial is to test a culturally adapted mindfulness-based stress reduction intervention in a community setting for African American adults with high blood pressure (hypertension) and depression. The main questions it aims to answer are:
* Does participation in a culturally adapted mindfulness-based intervention improve depressive symptoms?
* Does participation in a cultura…
The goal of this clinical trial is to test a culturally adapted mindfulness-based stress reduction intervention in a community setting for African American adults with high blood pressure (hypertension) and depression. The main questions it aims to answer are:
* Does participation in a culturally adapted mindfulness-based intervention improve depressive symptoms?
* Does participation in a culturally adapted mindfulness-based intervention improve blood pressure control?
* Is the intervention acceptable, appropriate, and feasible as delivered in a community setting?
Participants will:
* Participate in an 8-week group-based mindfulness intervention (CALM-Chicago). During intervention sessions, participants will learn about mindfulness and stress management and complete mindfulness-based activities, such as guided deep breathing and meditation.
* Complete surveys online
* Have their blood pressure measured with a non-invasive blood pressure cuff
* Attend 1 focus group (optional)
Trial Locations
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City
State
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Eligibility Criteria
Inclusion Criteria:
* ≥18 years old
* Lives, works, or spends much of their time in the South Side of Chicago neighborhood
* Self-reports diagnosis of hypertension or high blood pressure by a clinician
* Endorses elevated depressive symptoms as Patient Health Questionnaire (PHQ)-9 scores ≥10
* Not …
Inclusion Criteria:
* ≥18 years old
* Lives, works, or spends much of their time in the South Side of Chicago neighborhood
* Self-reports diagnosis of hypertension or high blood pressure by a clinician
* Endorses elevated depressive symptoms as Patient Health Questionnaire (PHQ)-9 scores ≥10
* Not taking antidepressant medication or stable on antidepressant medication for ≥6 months as self-reported
Exclusion Criteria:
* \<18 years old
* Severe mental illness (e.g., bipolar disorder, psychosis)
* Current suicidal ideation (PHQ-9 item 9) or recent (past 6 months) suicide attempt
* Unable to provide informed consent or complete study activities in English
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