Management of Post-operative Respiratory Failure by Using NIV and High Velocity Nasal Insufflation (HVNI)
Recruiting
N/A
Interventional Study
Respiratory Failure Without Hypercapnia
Respiratory Failure With Hypercapnia
Postoperative Respiratory Complication
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
At a Glance
- Age
- 18 and older
- Sex
- Any
- Study type
- Interventional
- Purpose
- Supportive Care
- Participants needed
- 180 (estimated)
- Sponsor
- Assiut University · Other
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About This Trial
Postoperative respiratory failure (PORF) remains a critical driver of morbidity, mortality, and incremental care costs in surgical populations. Traditional escalation often involves invasive mechanical ventilation, which is associated with ventilator-associated pneumonia (VAP), prolonged intensive care unit (ICU) stays, and increased resource burden.
Trial Locations
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Eligibility Criteria
Inclusion criteria:
* Age above 18 years
* within 48 hours after major surgery
* PAO2/FIO2 less than 200
* Signs of respiratory distress and respiratory rate (RR) more than 25 cycles/minute
Exclusion Criteria:
* Age below 18 years
* Pregnant ladies
* Orofacial trauma or burns
* Active Gastrointes…
Contacts