Dexamethasone Palmitate for PONV After Craniotomy
Recruiting
N/A
Interventional Study
Postoperative Nausea and Vomiting
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
At a Glance
- Age
- 18 – 65
- Sex
- Any
- Study type
- Interventional
- Purpose
- Prevention
- Participants needed
- 500 (estimated)
- Sponsor
- Beijing Tiantan Hospital · Other
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About This Trial
Dexamethasone is almost one of the most commonly used drugs for postoperative nausea and vomiting (PONV) prevention. However, PONV is still a complex problem to be solved; for example, even with preoperative dexamethasone administration, there are still some patients undergoing craniotomy still experience PONV within 24 hours postoperatively. Compared to dexamethasone, dexamethasone palmitate has …
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Aged 18 to 65 years;
* Providing written informed consent;
* Perform elective craniotomy undergoing general anesthesia.
Exclusion Criteria:
* Known to be allergic to dexamethasone;
* Any systemic glucocorticoids within 3 months before trial entry;
* History of severe heart d…
Contacts