Non-Invasive Brain Stimulation for Spinal Cord Injury
MEP Up-conditioning to Target Corticospinal Plasticity
Recruiting
Early Phase 1
Interventional Study
Spinal Cord Injury
Tetraplegia/Tetraparesis
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
At a Glance
- Age
- 18 and older
- Sex
- Any
- Trial phase
- Early Phase 1
- Study type
- Interventional
- Purpose
- Treatment
- Participants needed
- 11 (estimated)
- Sponsor
- Medical University of South Carolina · Other
Who this trial is looking for
This trial is looking for adults with a cervical spinal cord injury. Participants will undergo a 10-week program involving brain stimulation and muscle response training.
Are You a Good Fit for This Trial?
You may be able to join if
- I am an adult aged 18 or older.
- I have a history of spinal cord injury at or above the C6 level.
- It has been more than 6 months since my spinal cord injury.
- I have weak wrist extension on at least one side.
- I expect my current medications to stay the same for at least 3 months.
You may not be able to join if
- I have a motoneuron injury.
- I have a medically unstable condition.
- I have cognitive impairment.
- I have a history of epileptic seizures.
- I have metal implants in my skull.
- I have an implanted biomedical device in or above my chest.
- I use functional electrical stimulation on my arm every day.
- I am currently pregnant.
Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.
Think this trial could be right for you?
Answer a few quick questions to see if you may meet the eligibility requirements.
Check Your Eligibility
About This Trial
Individuals with chronic cervical spinal cord injury will complete a 10-week training protocol where participants receive non-invasive brain stimulation and feedback on the size of the corresponding muscle response (wrist extensor).
Investigators will assess the impact of the brain stimulation training on 1) the brain-to-spinal cord-to-muscle connection and 2) motor functions of the arm and hand.…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Adult (≥18 yrs old)
* A history of injury to spinal cord at or above C6
* \>6 months post SCI
* Weak wrist extension at least unilaterally
* Expectation that current medication will be maintained without change for at least 3 months. Stable use of anti-spasticity medication (e…
Contacts