Effect of Dexmedetomidine on Microsurgery Reconstruction in Cancer Patient
Recruiting
N/A
Interventional Study
Flap Monitoring
Inflammation
Thrombosis
Oxidative Stress
Glycocalyx
Anesthesia
Surgery
Flap Ischemia
Flap Necrosis
Flap Failure Risk Factors
Microsurgery
At a Glance
- Age
- 18 – 65
- Sex
- Any
- Study type
- Interventional
- Purpose
- Treatment
- Participants needed
- 60 (estimated)
- Sponsor
- Dharmais National Cancer Center Hospital · Government
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About This Trial
This double-blinded randomized controlled trial aims to investigate the effect of intraoperative dexmedetomidine administration on early flap viability and microvascular integrity in cancer patients undergoing elective microvascular reconstructive surgery. The primary outcome is clinical flap viability within 48 hours postoperatively, assessed using a standardized scoring system based on flap colo…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
1. Adult patients (aged 18-65 years) diagnosed with cancer who are scheduled to undergo microsurgical flap reconstruction.
2. Patients within the age range of 18 to 65 years at the time of enrollment.
3. Patients who provide written informed consent to participate in the study.
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Contacts