Quadriceps Motor Unit Adaptation to Simulated Knee Injury
Recruiting
Early Phase 1
Interventional Study
Muscle Inhibition
Knee Injury Simulation
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
At a Glance
- Age
- 18 – 30
- Sex
- Any
- Trial phase
- Early Phase 1
- Study type
- Interventional
- Purpose
- Basic Science
- Participants needed
- 45 (estimated)
- Sponsor
- University of Central Florida · Other
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About This Trial
This study investigates how simulated knee injury-via artificial joint effusion or deafferentation-affects quadriceps motor unit behavior in healthy young adults. Participants will complete neuromuscular testing during a single 2-hour lab session. This research seeks to improve understanding of muscle inhibition and inform interventions after real-world knee trauma.
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
1. Age 18-30 years
2. Physically active (Tegner ≥ 5)
3. No prior lower-limb surgery or major injury
Exclusion Criteria:
1. Lower limb surgery or significant injury in past 2 years
2. Cardiopulmonary, neurological, or psychiatric disorders
3. Needle/electrical stimulation anxie…
Contacts