Exploring the Utility of [18F]3F4AP for Demyelination Imaging

Recruiting Phase 1 Interventional Study
Demyelinating Disorders MCI Alzheimer's Disease (AD) MS (Multiple Sclerosis) SCI - Spinal Cord Injury Spinal Radiculopathy
No Placebo Group Every participant receives an active treatment — no one gets a placebo. Healthy Volunteers Welcome You do not need to have the condition being studied to take part.
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At a Glance
Age
18 – 90
Sex
Any
Trial phase
Phase 1
Study type
Interventional
Purpose
Diagnostic
Participants needed
105 (estimated)
Sponsor
Yale University · Other
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About This Trial

The overall objective is to obtain an assessment of the pharmacokinetics of \[18F\]3F4AP in healthy volunteers and subjects with demyelinating diseases such as mild cognitive impairment (MCI), Alzheimer's Disease (AD), Multiple Sclerosis (MS), Spinal Cord Injury (SCI) and Spinal radiculopathy (SR).

Trial Locations
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Eligibility Criteria
Inclusion: 1. Male and Female subjects must be ≥18 and \<90 years of age; 2. Able to understand and provide informed consent prior to study procedures 3. Must be in good health Exclusion: 1. Less than 18 years of age; 2. Pregnant or breastfeeding; 3. Any significant systemic illness or unstable m…
Contacts

Shannan Henry

+1 (203) 737-5278

shannan.henry@yale.edu

CONTACT

Kayla Cottiers

203-737-7496

kayla.cottiers@yale.edu

CONTACT