No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Ready to participate?
Review the details below, then apply to join this clinical trial.
At a Glance
Age
18 and older
Sex
Any
Study type
Interventional
Purpose
Treatment
Participants needed
1,618 (estimated)
Sponsor
University of Pittsburgh · Other
Who this trial is looking for
This trial is looking for adults who have had a cardiac arrest outside of the hospital and were resuscitated. Participants will receive usual medical care and may be transferred to a specialized hospital for better recovery.
Are You a Good Fit for This Trial?
You may be able to join if
I have had a cardiac arrest outside of the hospital.
I was resuscitated and have a pulse in the emergency department.
I received treatment at one of the participating hospital emergency departments.
I am at least 18 years old.
You may not be able to join if
I have prior advanced directives or requested limited critical care.
I had a dependent functional status before the cardiac arrest.
My arrest happened in the emergency department more than 4 hours after arrival.
The cause of my cardiac arrest was traumatic.
I have opted-out from the SPARC trial.
Summarized in plain language from this trial's official eligibility criteria.
The full criteria are further down this page — only the research team can
confirm whether you qualify.
Think this trial could be right for you?
Answer a few quick questions to see if you may meet the eligibility requirements.
This randomized clinical trial will determine if adult participants who are in the emergency department after being resuscitated from a cardiac arrest outside of the hospital benefit from care delivered at specialized centers.
The main question that it will answer is whether transferring participants to a hospital with a specialized cardiac arrest service improves recovery of function after 90 da…
This randomized clinical trial will determine if adult participants who are in the emergency department after being resuscitated from a cardiac arrest outside of the hospital benefit from care delivered at specialized centers.
The main question that it will answer is whether transferring participants to a hospital with a specialized cardiac arrest service improves recovery of function after 90 days.
Participants will receive all usual medical care, but some participants will be offered transfer to a regional cardiac arrest center and others will be offered care at the closest appropriate hospital. Investigators will interview participants after 90 days to assess their recovery.
Trial Locations
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Facility
City
State
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Status
Eligibility Criteria
Inclusion Criteria:
* Out-of-hospital cardiac arrest
* Resuscitated from cardiac arrest with palpable pulse in the emergency department
* Treated at one of participating hospital emergency departments
* Age ≥18 years
Exclusion Criteria:
* Known prior advanced directives or decision to limit criti…
Inclusion Criteria:
* Out-of-hospital cardiac arrest
* Resuscitated from cardiac arrest with palpable pulse in the emergency department
* Treated at one of participating hospital emergency departments
* Age ≥18 years
Exclusion Criteria:
* Known prior advanced directives or decision to limit critical care
* Known pre-arrest dependent functional status (e.g., living in a skilled nursing facility, hospice or bedbound)
* Arrest in the emergency department \>4 hours after arrival
* Traumatic etiology of arrest
* Known to have opted-out from the SPARC trial
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