Study of CM518D1 in Patients With Advanced Solid Tumors

Inclusion Criteria: * 1\. Male or female ≥ 18 and ≤75 years of age. * 2\. Subjects with histologically or cytologically confirmed advanced solid tumors. * 3\. At least one measurable lesion according to RECIST v1.1. * 4\. Expected survival time ≥ 3 months as judged by the Investigator. Exclusion Criteria: * 1\. Subjects who have received any chemotherapy or any drug therapy for antitumor treatment including monoclonal antibodies, targeted therapy, radioimmunoconjugates, or Antibody-Drug Conjugates(ADCs), or any investigational product therapy for anti-tumor therapy within 28 days prior to the first dose or within 5 half-lives (whichever is shorter). * 2\. Subjects who have received major surgery within 28 days prior to the first dose. * 3\. Subjects who have received radiotherapy within 21 days prior to the first dose. * 4\. Subjects who have received systemic glucocorticoid therapy (more than 10 mg of prednisone or equivalent daily) or other forms of immunosuppressive therapy within 7 days prior to the first dose. * 5\. Subjects who have received any CDH17-targeted therapy. * 6\. History of other malignancies within 5 years prior to the first dose, excluding cured basal or squamous cell carcinoma of skin, carcinoma cervix in situ, or breast ductal carcinoma in situ. * 7\. Hypersensitivity to the investigational drug or its excipients. * 8\. Pregnant or lactating female patients.