PSMA PET for the Staging and Management of Hepatocellular Carcinoma

Recruiting Observational Study
Hepatocellular Carcinoma (HCC)
No Placebo Group Every participant receives an active treatment — no one gets a placebo. No Study Drug Researchers observe your health over time — no experimental treatment is given.
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At a Glance
Age
18 and older
Sex
Any
Study type
Observational
Participants needed
90 (estimated)
Sponsor
VA Office of Research and Development · Federal
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About This Trial
This prospective, single-center study evaluates the clinical utility of F18-Piflufolastat (PSMA) PET/CT when added to conventional cross-sectional imaging for patients with suspected or confirmed hepatocellular carcinoma (HCC). The study aims to determine whether PSMA PET/CT improves diagnostic accuracy for indeterminate liver lesions (LI-RADS 3 and 4), enhances staging precision in treatment-naïv…
Trial Locations
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Eligibility Criteria
Inclusion Criteria: * Adult patients age \>18 years from the VA medical system * Treatment-naïve patients with HCC with BCLC B or C disease Exclusion Criteria: * Patients with renal dysfunction or contrast allergy that precludes contrast enhanced cross sectional imaging * Patients with presence o…
Contacts

Binu V John, MD MPH

(305) 575-7000

binu.john@va.gov

CONTACT

Flavia R Carneiro, PhD

(305) 575-7762

flavia.carneiro@va.gov

CONTACT