The Million Anesthesia Cases Study (MACS) - a Cohort Study of Preoperative Fasting and Perioperative Outcomes

Recruiting Observational Study
Anesthesia Sedation Monitored Anesthesia Care Procedure Surgery, Day Surgery Surgery Scheduled Fasting Before Operation Aspiration; Gastric Contents, Anesthesia
No Placebo Group Every participant receives an active treatment — no one gets a placebo. No Study Drug Researchers observe your health over time — no experimental treatment is given.
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At a Glance
Sex
Any
Study type
Observational
Participants needed
1,200,000 (estimated)
Sponsor
Massachusetts General Hospital · Other
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About This Trial
Perioperative fasting has historically been viewed as a low-risk intervention. However, preliminary data indicate that perioperative loss of nutrition and fluids is likely harmful. This study intends to characterize perioperative fasting practices and their potential effects on clinical outcomes through possible effects on patient well-being (anxiety, hunger, thirst), physiology (hypovolemia, hypo…
Trial Locations
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Eligibility Criteria
Inclusion Criteria: * Diagnostic or therapeutic procedure with anesthesia care (general anesthesia, regional anesthesia, sedation, or a combination of the above) Exclusion Criteria: * Not receiving anesthesia care * Lack of medical record data in Epic electronic medical record system
Contacts

Alexander Nagrebetsky, MD, MSc

617-724-3292

anagrebetsky@mgh.harvard.edu

CONTACT