Postpartum Evaluation of Nifedipine and Enalapril for Hypertension

Recruiting Phase 4 Interventional Study
Hypertension in Pregnancy
No Placebo Group Every participant receives an active treatment — no one gets a placebo. Prior Safety Data This treatment has already been tested in at least one earlier human trial.
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At a Glance
Age
19 and older
Sex
Female
Trial phase
Phase 4
Study type
Interventional
Purpose
Treatment
Participants needed
850 (estimated)
Sponsor
Nebraska Methodist Health System · Other
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About This Trial
This is an open label, randomized controlled trial designed to compare nifedipine and enalapril in the management of postpartum hypertension. This is an equivalence study- meaning it is not expected one medication is better than the other. Nifedipine has been shown to be better than another common blood pressure medicine, labetalol, for postpartum hypertension but enalapril which is also used worl…
Trial Locations
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Eligibility Criteria
Inclusion Criteria: 1. admitted for delivery by cesarean or vaginal delivery 2. 24 weeks gestation or greater 3. Pregnancy related hypertension(HTN) or chronic hypertension. Pregnancy related hypertension will be defined during the study as either a systolic blood pressure ≥140mmHg or diastolic blo…
Contacts

Todd Lovgren, MD

14028151970

todd.lovgren@nmhs.org

CONTACT

Joshua Dahlke, MD

14028151970

joshua.dahlke@nmhs.org

CONTACT