A Study of Reduced Dose Radiation Therapy for People With B-Cell Lymphomas

Recruiting Phase 3 Interventional Study
Follicular Lymphoma Marginal Zone Lymphoma
No Placebo Group Every participant receives an active treatment — no one gets a placebo. Pivotal Trial This treatment is in the last trial phase before FDA approval. Prior Safety Data This treatment has already been tested in at least one earlier human trial.
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At a Glance
Age
18 and older
Sex
Any
Trial phase
Phase 3
Study type
Interventional
Purpose
Treatment
Participants needed
375 (estimated)
Sponsor
Memorial Sloan Kettering Cancer Center · Other
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About This Trial
The researchers are doing this study to find out whether a very low dose of radiation therapy (VLDRT) is an effective treatment for people with follicular lymphoma (FL) or marginal zone lymphoma (MZL) and works as well as the standard dose of radiation therapy. The researchers will see if VLDRT works against cancer in the area that is currently affected by cancer and if the therapy prevents new sp…
Trial Locations
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Eligibility Criteria
Inclusion Criteria: (Arms 1\&2) * Patients must be diagnosed with a follicular lymphoma or marginal zone lymphoma. Of note, there are now two widely-utilized pathology classification criteria used for mature B-cell lymphomas, the World Health Organization (WHO) 5th Edition Classification of Lymphoi…
Contacts

Brandon Imber, MD

631-212-6346

imberb@mskcc.org

CONTACT

Joachim Yahalom, MD

646-608-2639

CONTACT