NGM120 for Colorectal Cancer with Cachexia

An Evaluation of NGM120 in a Randomized, Double-blind, Placebo-controlled Study in Participants With Colorectal Cancer Who Have Cancer Cachexia.

Recruiting Phase 2 Interventional Study
Colorectal Cancer CRC (Colorectal Cancer) Cancer Cachexia
Prior Safety Data This treatment has already been tested in at least one earlier human trial.
Ready to participate?

Review the details below, then apply to join this clinical trial.

At a Glance
Age
18 and older
Sex
Any
Trial phase
Phase 2
Study type
Interventional
Purpose
Treatment
Participants needed
136 (estimated)
Sponsor
NGM Biopharmaceuticals, Inc · Industry
Who this trial is looking for

This trial is looking for people with colorectal cancer who are also experiencing weight loss due to cachexia. Participants will receive either the study drug NGM120 or a placebo to see how it affects their condition.

Are You a Good Fit for This Trial?

You may be able to join if

  • I have been diagnosed with colorectal cancer.
  • I have significant weight loss that fits cachexia criteria.
  • I have signed the informed consent form.

You may not be able to join if

  • I have active issues that are affecting my appetite.
  • I am currently receiving tube feedings or nutrition through an IV.
  • I have cachexia from causes other than my cancer.

Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.

Think this trial could be right for you?

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About This Trial

A multi-center evaluation of NGM120 in a randomized, double-blind, placebo-controlled study in participants with colorectal cancer who have cancer cachexia.

Trial Locations
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Eligibility Criteria
Inclusion Criteria: 1. Documented active diagnosis of colorectal cancer. 2. Cachexia defined by Fearon criteria of weight loss. 3. Signed informed consent. Exclusion Criteria: 1. Current active reversible causes of decreased food intake. 2. Receiving tube feedings or parenteral nutrition at the t…
Contacts

NGM Study Director

650-727-8800

NGM120CX@ngmbio.com

CONTACT