Natural History of Advanced Chronic Liver Diseases

Recruiting Observational Study
Cirrhosis Advanced Chronic Liver Disease
No Placebo Group Every participant receives an active treatment — no one gets a placebo. No Study Drug Researchers observe your health over time — no experimental treatment is given.
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At a Glance
Age
18 and older
Sex
Any
Study type
Observational
Participants needed
500 (estimated)
Sponsor
Chinese University of Hong Kong · Other
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About This Trial

This is a retrospective-prospective registry cohort study. Patients with advanced chronic liver disease (ACLD) will be prospectively invited to this study. The study follow-up duration will be 10 years. The primary outcome is incident hepatic events and liver-related mortality. Participants will undergo annual transient elastography examination.

Trial Locations
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Eligibility Criteria
Inclusion Criteria: * Aged 18 or above * Known ACLD, defined by: * LSM \> 10kPa or * Clinical cirrhosis, suggested by 1. ultrasonography of the hepatobiliary system shows features of cirrhosis (e.g. shrunken and nodular liver) and portal hypertension (e.g. dilated portal vein, portal-systemic …
Contacts

Jimmy CT Lai, MB ChB

85235054205

jimmyctlai@cuhk.edu.hk

CONTACT

Angel Chim, MSc

85235054205

angelchim@cuhk.edu.hk

CONTACT