No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
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At a Glance
Age
18 – 39
Sex
Any
Study type
Interventional
Purpose
Treatment
Participants needed
30 (estimated)
Sponsor
Freda Patterson · Other
Who this trial is looking for
This trial is looking for young adults ages 18-39 with elevated blood pressure. Participants will exercise at different times of the day and have their blood pressure monitored over 24 hours to see how timing affects their blood pressure.
Are You a Good Fit for This Trial?
Rules you outObstructive sleep apneaInsomniaRestless leg syndrome
You may be able to join if
I am 18 to 39 years old
My resting blood pressure is between 120/80 mmHg and 140/90 mmHg
You may not be able to join if
I have a chronic or autoimmune disease
I have a history of sleep disorders
I have alcohol or drug dependence
I am normotensive or have stage 2+ hypertension
My body mass index is less than 18.5 or greater than 35 kg/m2
I use sleep medications or supplements
I am highly physically active
I am currently pregnant or breastfeeding
Summarized in plain language from this trial's official eligibility criteria.
The full criteria are further down this page — only the research team can
confirm whether you qualify.
Think this trial could be right for you?
Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.
The goal of this study is to learn how exercise timing affects blood pressure in adults with elevated or high blood pressure. Exercise can influence the body's natural 24-hour rhythms, including blood pressure patterns. A single exercise session can lower blood pressure for up to 24 hours, but it is not fully understood how the time-of-day for exercise affects this response. The main question this…
The goal of this study is to learn how exercise timing affects blood pressure in adults with elevated or high blood pressure. Exercise can influence the body's natural 24-hour rhythms, including blood pressure patterns. A single exercise session can lower blood pressure for up to 24 hours, but it is not fully understood how the time-of-day for exercise affects this response. The main question this study aims to answer is:
• When the same participant exercises at different times of day (morning, afternoon, or evening), how does this affect the participant's blood pressure over the next 24 hours?
Participants will:
* Undergo an in-lab assessment of individual biological rhythm that will indicate the clock-time for an individual's biological night
* Complete 3 supervised treadmill exercise sessions
* 1 in the biological morning (biological night + 10 hours)
* 1 in the biological afternoon (biological night + 15 hours)
* 1 in the biological evening (biological night + 20 hours)
* Complete a 24-hour blood pressure assessment before and after each exercise session
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* 18-39 Years old
* Resting blood pressure greater than or equal to 120/80 mmHg or less than 140/90 mmHg
Exclusion Criteria:
* Diagnosis or history of chronic or autoimmune disease (i.e., cardiovascular, metabolic, renal, endocrine, cancer)
* Diagnosis or history of sleep diso…
Inclusion Criteria:
* 18-39 Years old
* Resting blood pressure greater than or equal to 120/80 mmHg or less than 140/90 mmHg
Exclusion Criteria:
* Diagnosis or history of chronic or autoimmune disease (i.e., cardiovascular, metabolic, renal, endocrine, cancer)
* Diagnosis or history of sleep disorder (i.e., obstructive sleep apnea, insomnia, restless leg syndrome)
* Alcohol or drug dependence
* Elevated risk for sleep disorders
* Elevated risk for clinical depression
* Normotensive (blood pressure less than 120/80 mmHg) or stage 2+ hypertension (blood pressure greater than or equal to 140/90 mmHg)
* Body mass index less than 18.5 or greater than 35 kg/m2
* Self-reported use of sleep medications/supplements (e.g., melatonin)
* Self-reported use of medications influencing vascular physiology (e.g., antihypertensive medications, weight loss medications)
* Highly physically active (greater than or equal to 300 minutes moderate-to-vigorous physical activity per week)
* Currently pregnant or breastfeeding
* Current tobacco use (greater than or equal to 1 cigarette in the past month)
* Nighttime or rotating shift work within the last 3 months
* Contraindications to aerobic exercise
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