Monitoring Patients With Repetitive Head Impact With Gamma-glutamylcysteine Supplementation

Recruiting Phase 1 Interventional Study
Repetitive Head Impacts
No Placebo Group Every participant receives an active treatment — no one gets a placebo.
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At a Glance
Age
30 – 70
Sex
Any
Trial phase
Phase 1
Study type
Interventional
Purpose
Prevention
Participants needed
30 (estimated)
Sponsor
Pravat Mandal · Other
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About This Trial
The goal of this clinical trial is to test whether the gamma - glutamylcystiene (GGC) oral supplement can reach the brain and subsequently increase antioxidant glutathione (GSH) level in people with repetitive head impact (RHI). This will reduce the oxidative stress related injury in people with RHI.This unique study's main objective is to test the: 1. Change in GSH in brain and blood levels thro…
Trial Locations
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Eligibility Criteria
Inclusion Criteria: * Retired NFL player, retired Navy SEAL/army personnel with combat experience exposed to repetitive head impact; * Memory and behavioral complaint per self- or informant-report; * Age (30 to 70 years of age) years; * Able to read and write in English and to give consent to parti…
Contacts

Pravat K MANDAL, PHD

4126999561

mandalpk@pitt.edu

CONTACT