Combined Genetic Testing for Cancer Risk During Pregnancy
Trial of Combined Obstetric Carrier Screening and Hereditary Cancer Screening
Recruiting
N/AInterventional Study
Hereditary Cancer Syndromes
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Ready to participate?
Review the details below, then apply to join this clinical trial.
At a Glance
Age
18 – 55
Sex
Female
Study type
Interventional
Purpose
Prevention
Participants needed
550 (estimated)
Sponsor
Weill Medical College of Cornell University · Other
Who this trial is looking for
This trial is looking for pregnant women or those planning to become pregnant who are interested in genetic testing for cancer risk. Participants will receive cancer risk screening alongside standard prenatal genetic tests.
Are You a Good Fit for This Trial?
You may be able to join if
I am between 18 and 55 years old.
I am pregnant or receiving fertility care.
I can speak and read in English or Spanish.
I have chosen to undergo genetic screening with my doctor.
You may not be able to join if
I have already completed a multigene cancer panel.
I have a blood cancer or a pre-cancer condition.
I have had a bone marrow transplant.
Summarized in plain language from this trial's official eligibility criteria.
The full criteria are further down this page — only the research team can
confirm whether you qualify.
Think this trial could be right for you?
Answer a few quick questions to see if you may meet the eligibility requirements.
The investigators hypothesize that pregnancy and preconception care may be a feasible and effective time to offer inherited cancer risk screening. This study will assess interest in cancer genetic testing among patients receiving routine prenatal or preconception/fertility care. The goal is to evaluate the acceptability of BRCA1/2 testing when offered alongside standard prenatal genetic screening.…
The investigators hypothesize that pregnancy and preconception care may be a feasible and effective time to offer inherited cancer risk screening. This study will assess interest in cancer genetic testing among patients receiving routine prenatal or preconception/fertility care. The goal is to evaluate the acceptability of BRCA1/2 testing when offered alongside standard prenatal genetic screening. The study will also explore whether universal screening in this population could support early cancer prevention and be cost-effective, especially among underserved populations.
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Age 18 years - 55 years
* Pregnant patients receiving obstetrical-related care or receiving preconception/fertility care at a WCM-affiliated enrollment site.
* Patients who have elected to undergo OCS with the WCM-affiliated obstetrics provider
* Patients with prior OCS but pl…
Inclusion Criteria:
* Age 18 years - 55 years
* Pregnant patients receiving obstetrical-related care or receiving preconception/fertility care at a WCM-affiliated enrollment site.
* Patients who have elected to undergo OCS with the WCM-affiliated obstetrics provider
* Patients with prior OCS but planned to repeat OCS are eligible
* Patients can speak and read in English or Spanish
Exclusion Criteria:
* Patients who have previously completed a multigene hereditary cancer syndrome panel
* Patients who have a hematologic cancer or hematologic pre-cancer
* Patients who have a history of an autologous bone marrow transplant
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