UPBEAT: Using Polygenic Scores to Guide BB Therapy in HF With Mildly Reduced EF
Recruiting
N/A
Interventional Study
Heart Failure
Polygenic Score
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
At a Glance
- Age
- 18 – 89
- Sex
- Any
- Study type
- Interventional
- Purpose
- Treatment
- Participants needed
- 10 (estimated)
- Sponsor
- David Lanfear · Other
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About This Trial
This study will use polygenic scores, a tool which describes differences in genetics, to examine effectiveness of beta blocker medication in heart failure patients with ejection fraction of 41-50 percent. The study will also assess beta blockers' effect on the changes in left ventricular end-systolic volume index by MRI.
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Age 18-89 years
* Ejection Fraction (EF) \>40% and =\<50% by any modality within 1 year (must be most recent)
* Clinical diagnosis of HF within 1 year, evidenced by any one: Hospital discharge with primary or secondary HF diagnosis, ER discharge with primary diagnosis of HF, a…
Contacts