SGLT2i in Kidney Stones
Recruiting
Early Phase 1
Interventional Study
Kidney Stones
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
At a Glance
- Age
- 18 – 70
- Sex
- Any
- Trial phase
- Early Phase 1
- Study type
- Interventional
- Purpose
- Treatment
- Participants needed
- 32 (estimated)
- Sponsor
- University of Chicago · Other
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About This Trial
This study is looking at whether empagliflozin, a medication typically used for diabetes and heart conditions, may affect factors that contribute to kidney stone formation. The research focuses on people who have had calcium-based kidney stones, i.e. calcium oxalate or calcium phosphate stones.
Previous studies in those without kidney stones found that empagliflozin increased urinary citrate leve…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
Calcium phosphate (CaP) stone participants:
* Age 18-70
* History of at least one calcium phosphate (hydroxyapatite) stone
* Defined as at least 50% of stone material on most recent stone analysis
Calcium oxalate (CaOx) stone participants:
* Age 18-70
* History of at least…
Contacts
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