CMA2 Supplement for Alzheimer's Disease

Combined Metabolic Activator Supplementation in Subjects Diagnosed With Alzheimer's Disease

Recruiting Phase 3 Interventional Study
Alzheimer Disease
Pivotal Trial This treatment is in the last trial phase before FDA approval. Prior Safety Data This treatment has already been tested in at least one earlier human trial.
Ready to participate?

Review the details below, then apply to join this clinical trial.

At a Glance
Age
50 and older
Sex
Any
Trial phase
Phase 3
Study type
Interventional
Purpose
Supportive Care
Participants needed
845 (estimated)
Sponsor
ScandiBio Therapeutics AB · Industry
Who this trial is looking for

This trial is looking for adults aged 50 and older who have been diagnosed with Alzheimer's Disease. Participants will take a supplement or a placebo twice a day for 26 weeks and visit the clinic four times for checkups and tests.

Are You a Good Fit for This Trial?

You may be able to join if

  • I am at least 50 years old.
  • I have been diagnosed with Alzheimer's Disease.
  • My Alzheimer's treatment and condition have been stable for at least 1 month.
  • I can provide written consent to participate.

You may not be able to join if

  • I have a history of stroke.
  • I have had brain trauma in the last 14 days.
  • I have uncontrolled depression.
  • I have uncontrolled diabetes.
  • I have serious swallowing problems.
  • I have chronic kidney disease.
  • I have a known allergy to study substances.
  • I have participated in another clinical study in the last 3 months.

Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.

Think this trial could be right for you?

Answer a few quick questions to see if you may meet the eligibility requirements.

Check Your Eligibility
About This Trial
This randomised, double-blinded, placebo-controlled study aims to establish metabolic improvements in subjects diagnosed with Alzheimer's Disease (AD) by treatment with CMA2 including N-acetyl-L-cysteine (NAC), L-carnitine-L-tartrate (LCAT), nicotinamide (niacinamide), and L-serine. Participants will take the drug CMA2 or a placebo twice a day for 26 weeks. They will visit the clinic 4 times for …
Trial Locations
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Eligibility Criteria
Inclusion Criteria: 1. Men and women of non-childbearing potential ≥ 50 years of age. 2. Diagnosed with AD and at the Screening visit having the scores of ADAS-Cog ≥ 12 and GDS≥ 4. 3. Stable AD treatments and clinical course for at least 1 month. 4. Females of childbearing potential must have docum…
Contacts

Sevki SAHIN, Prof. Dr.

+90 216 606 33 00

drsahin@gmail.com

CONTACT

Ozlem Totuk, Dr.

+90 216 606 33 00

totukozlem@gmail.com

CONTACT