The Effect of Asymmetrical vs. Symmetrical High Flow Nasal Cannula on the Work of Breathing

Recruiting N/A Interventional Study
Respiratory Disease (Clinically Stable Individuals - Patients Recovered From Respiratory Disease)
No Placebo Group Every participant receives an active treatment — no one gets a placebo. Healthy Volunteers Welcome You do not need to have the condition being studied to take part.
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At a Glance
Age
18 and older
Sex
Any
Study type
Interventional
Purpose
Basic Science
Participants needed
30 (estimated)
Sponsor
Larissa University Hospital · Other
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About This Trial
The goal of this study randomized single-center crossover study is to evaluate the impact of asymmetrical versus symmetrical nasal high flow (NHF) therapy on work of breathing (WOB). The main question it aims to answer are: 1\. Does the asymmetrical NHF interface improve the work of breathing compared to the symmetrical NHF interface? Researchers will compare the symmetrical NHF interface to the …
Trial Locations
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Eligibility Criteria
Inclusion Criteria: 1. age ≥18 years old 2. absence of symptoms and signs of respiratory failure (SpO2\>95% at FiΟ2 0.21) Exclusion Criteria: 1. pregnancy 2. SpO2\<94% at FiΟ2 0.21 3. neuromuscular disease 4. contraindications to esophageal pressure monitoring (e.g., uncontrolled coagulopathy, es…
Contacts

Ioannis Dr. Pantazopoulos, Associate Professor

+30- 6945661525

pantazopoulosioannis@yahoo.com

CONTACT