Evaluate the Benefit of Corticoid Sparing in Elderly With Generalized AntiRAch Myasthenia Gravis Treated With IV or SC Efgartigimod

Recruiting Phase 4 Interventional Study
Myasthenia Gravis, Generalized
No Placebo Group Every participant receives an active treatment — no one gets a placebo. Prior Safety Data This treatment has already been tested in at least one earlier human trial.
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At a Glance
Age
65 and older
Sex
Any
Trial phase
Phase 4
Study type
Interventional
Purpose
Prevention
Participants needed
50 (estimated)
Sponsor
Centre Hospitalier Universitaire de Nice · Other
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About This Trial
Generalized Myasthenia Gravis (gMG) is a rare chronic autoimmune disorder causing muscle weakness and fatigue, primarily due to autoantibodies that disrupt neuromuscular junction function. The most common antibodies target nicotinic acetylcholine receptors (AChR), with others such as anti-MuSK and anti-LRP4 being less prevalent. The conventional gMG treatments include acetylcholinesterase inhibito…
Trial Locations
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Eligibility Criteria
Inclusion Criteria: * Male or female subjects aged ≥65 years * Diagnosed with gMG with confirmed documentation and supported by a physical exam and confirmed seropositivity for AChR-Abs. * Meets the clinical criteria as defined by the Myasthenia Gravis Foundation of America (MFGA) for generalized M…
Contacts

Sabrina SACCONI, pu-ph

+33 (4) 92 03 57 57

sacconi.s@chu-nice.fr

CONTACT