Weekly Insulin Icodec for Type 1 Diabetes

A Research Study to See How a Weekly Insulin, Insulin Icodec, Helps in Reducing the Blood Sugar Compared to Daily Insulin Glargine, Both in Combination With Insulin Aspart, in Adults With Type 1 Diabetes

Recruiting Phase 3 Interventional Study
Diabetes Mellitus, Type 1
No Placebo Group Every participant receives an active treatment — no one gets a placebo. Pivotal Trial This treatment is in the last trial phase before FDA approval. Prior Safety Data This treatment has already been tested in at least one earlier human trial.
Ready to participate?

Review the details below, then apply to join this clinical trial.

At a Glance
Age
18 and older
Sex
Any
Trial phase
Phase 3
Study type
Interventional
Purpose
Treatment
Participants needed
877 (estimated)
Sponsor
Novo Nordisk A/S · Industry
Who this trial is looking for

This trial is looking for adults with type 1 diabetes to compare a new weekly insulin called insulin icodec with a daily insulin called insulin glargine. Participants will need to monitor their blood sugar levels during the study, which lasts about 8.5 months.

Are You a Good Fit for This Trial?
Must be taking Multiple daily insulin injections

You may be able to join if

  • I have been diagnosed with type 1 diabetes for at least 1 year.
  • I have been using multiple daily insulin injections for at least 6 months.
  • My HbA1c levels are between 7.0% and 10.0%.
  • I can and will follow the study procedures.

You may not be able to join if

  • I am known or suspected to be allergic to the study medicines.
  • I have participated in this trial before.
  • I am pregnant, breastfeeding, or planning to get pregnant.
  • I have taken any investigational medicines in the last 90 days.
  • I have any health condition that might affect my safety in the trial.
  • I plan to change any medications that could affect my weight or blood sugar.
  • I have hypoglycaemic unawareness.
  • I have had severe low blood sugar episodes in the past year.

Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.

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About This Trial

This study compares insulin icodec, an insulin taken once a week to insulin glargine, an insulin taken once a day. The study medicine will be investigated in participants with type 1 diabetes. The study will look at how well insulin icodec taken weekly controls blood sugar compared to insulin glargine taken daily. The study will last for about 8.5 months.

Trial Locations
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Eligibility Criteria
Inclusion Criteria: * Diagnosed with type 1 diabetes mellitus greater than or equal to (≥) 1 year before screening. * Treated with multiple daily insulin injections (daily basal insulin analogue and bolus insulin analogue regimen) ≥ 6 months before screening. * HbA1c from 7.0-10.0 percentage (%) (5…
Contacts

Novo Nordisk

(+1) 866-867-7178

clinicaltrials@novonordisk.com

CONTACT