MuScle WastIng and DysphaGia iN CriticAlly IlL Patients (SIGNAL)

Recruiting Observational Study
Critical Illness Dysphagia Muscle Wasting in Critically Ill Swallowing Disorders
No Study Drug Researchers observe your health over time — no experimental treatment is given.
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At a Glance
Age
18 and older
Sex
Any
Study type
Observational
Participants needed
160 (estimated)
Sponsor
Barts & The London NHS Trust · Other
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About This Trial
The goal of this study is to find out how muscle wasting in the mouth and throat affects swallowing (dysphagia) in adults who are critically ill and being treated in intensive care units. The main aims of this research study are to understand: how much and how quickly the oral and suprahyoid muscles waste in critically ill participants, and whether muscle wasting causes problems with swallowing. …
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Eligibility Criteria
Inclusion Criteria: * Adults \>18 years * Receiving mechanical ventilation via endotracheal tube and/or tracheostomy. Expected to receive ventilation for at least 72 hours. * Expected to survive admission and spend more than 7 days in the intensive care unit. Control participants * Adults \>18 ye…
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