Manipulating the Peri-Infarct Area Using Maraviroc to Enhance Motor Skills After Stroke

Recruiting Phase 2 Interventional Study
Ischemic Stroke Stroke Stroke Acute
Prior Safety Data This treatment has already been tested in at least one earlier human trial.
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At a Glance
Age
18 and older
Sex
Any
Trial phase
Phase 2
Study type
Interventional
Purpose
Treatment
Participants needed
80 (estimated)
Sponsor
Emmanuel Carrera · Other
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About This Trial

MASTER is a single-center, patient and investigator-blinded, Randomized Controlled Trial (RCT) to compare the efficacy of Maraviroc, a C-C chemokine receptor 5 (CCR5) antagonist, against placebo regarding motor function and motor learning skills in the first 3 months after ischemic stroke.

Trial Locations
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Eligibility Criteria
Inclusion Criteria: * Informed consent as documented by signature * ≥18 years at time of signing of informed consent * Acute ischemic stroke. * Stroke onset \< 7 days from randomization. * Contralateral, unilateral, incomplete upper limb paresis, incl. : * FMA-UE \< 63/66 * Residual voluntary finge…
Contacts

Emmanuel Carrera, MD

+41 (0)22 372 83 18

emmanuel.carrera@hug.ch

CONTACT

Nicolas Broc, MD

+41 (0)79 553 38 37

nicolas.broc@hug.ch

CONTACT