Sentinel Lymph Node Biopsy After Neoadjuvant Chemotherapy in IBC

Recruiting N/A Interventional Study
Invasive Breast Carcinoma Sentinel Lymph Node Biopsy (SLNB) Neoadjuvant Chemotherapy
No Placebo Group Every participant receives an active treatment — no one gets a placebo.
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At a Glance
Age
18 and older
Sex
Female
Study type
Interventional
Purpose
Treatment
Participants needed
75 (estimated)
Sponsor
European Institute of Oncology · Other
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About This Trial
This study will prospectively determine the feasibility and oncological safety of sentinel lymph node biopsy (SLNB) after neoadjuvant chemotherapy (NACT) in inflammatory breast cancer patients traditionally considered ineligible for SLNB due to locally advanced cancer with skin/chest wall involvement (cT4d) and heavy nodal burden at presentation (cN1/N2). This study will also assess the identifica…
Trial Locations
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Eligibility Criteria
Inclusion Criteria: * Female patients over 18 years of age with clinically and biopsy-proven stage IIIB cT4d cN0-2 M0 breast cancer as assessed by clinical exam and imaging * Patients receiving NACT and having a nodal complete clinical response (ycN0) as assessed by physical exam and imaging (ultra…
Contacts

Francesca Magnoni, MD

+39 0294371092

francesca.magnoni@ieo.it

CONTACT