Routine Validation and Reproducibility Testing of Laboratory Assays and Research Techniques Used for Endocrine, Cardiometabolic, and Musculoskeletal Disorder Research (VALD)
Recruiting
Observational Study
Obesity and Obesity-related Medical ConditionsDiabetesAtherosclerotic DiseaseHeart FailureMASHSarcopeniaOsteoporosisHyperparathyroidismHypoparathyroidismIschemic Heart DiseaseCystic Fibrosis (CF)Chronic Kidney Disease(CKD)OsteopeniaCachexia
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
Ready to participate?
Review the details below, then apply to join this clinical trial.
At a Glance
Age
18 – 100
Sex
Any
Study type
Observational
Participants needed
100 (estimated)
Sponsor
Bettina Mittendorfer · Other
Who this trial is looking for
This trial is looking for healthy adults or those with certain chronic conditions to help test the accuracy of lab tests and other techniques. Participation involves undergoing tests to see if results are consistent over time.
Are You a Good Fit for This Trial?
You may be able to join if
I am between 18 and 100 years old.
My body mass index is between 16.0 and 60 kg/m2.
You may not be able to join if
I am under 18 or over 100 years old.
My body mass index is below 16.0 or above 60 kg/m2.
I have dietary restrictions or allergies to meal ingredients.
I take medications or supplements that might affect the tests.
I exercise regularly for more than 150 minutes a week unless it's for the tests.
I have serious organ disease except for those being tested.
I have an alcohol use disorder or use controlled substances unless required for the tests.
I am pregnant, smoke, am a prisoner, or cannot give consent.
Summarized in plain language from this trial's official eligibility criteria.
The full criteria are further down this page — only the research team can
confirm whether you qualify.
Think this trial could be right for you?
Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.
The purpose of this research study is to validate (check the accuracy of) laboratory assays, intravenous catheter insertion, and equipment or devices and their reproducibility, which is necessary to perform high quality research on chronic diseases, nutrition, and metabolism (the process by which a substance is handled in the body) at the University of Missouri. As technology changes and uses new …
The purpose of this research study is to validate (check the accuracy of) laboratory assays, intravenous catheter insertion, and equipment or devices and their reproducibility, which is necessary to perform high quality research on chronic diseases, nutrition, and metabolism (the process by which a substance is handled in the body) at the University of Missouri. As technology changes and uses new testing methods, it is necessary to compare results from old tests, equipment and devices and new tests, equipment, or devices and the reproducibility of these measurements to make sure the results are accurate. Reproducibility means performing the same test more than once to see if the same results can be achieved each time. This study will look at the validation and reproducibility of tests and laboratory assays in participants who are healthy or affected by relevant endocrine, cardiometabolic, and musculoskeletal disorders.
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* ≥18 and ≤100 years of age
* body mass index ≥16.0 and ≤60 kg/m2
Exclusion Criteria:
* \<18 and \>100 years of age
* body mass index \<16.0 or \>60 kg/m2
* allergies, intolerances, or dietary restrictions to meal ingredients, vegans or vegetarians
* use of medications or diet…
Inclusion Criteria:
* ≥18 and ≤100 years of age
* body mass index ≥16.0 and ≤60 kg/m2
Exclusion Criteria:
* \<18 and \>100 years of age
* body mass index \<16.0 or \>60 kg/m2
* allergies, intolerances, or dietary restrictions to meal ingredients, vegans or vegetarians
* use of medications or dietary supplements (e.g., anti-inflammatories, immune modulators, etc) that could interfere with the particular assay/techniques being evaluated
* engaged in regular structured exercise \>150 min per week unless needed for validation of the assay/technique being evaluated
* significant organ system dysfunction or diseases, except those that are sought for validation of the assay/technique being evaluated
* alcohol use disorder as defined by the National Institute of Alcohol Abuse and Alcoholism or use of controlled substances unless alcohol use disorder is required for validation of the assay/technique being evaluated
* pregnant women, persons who smoke, prisoners, and inability to grant voluntary informed consent.
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