The multi-step thawing protocol with a reduction of non-permeable cryoprotectant concentrations to reduce osmotic shock caused by the rapid influx of water. Recent studies have shown that a simplified warming protocol by only a thawing solution gave a comparable survival rate but increased pregnancy rate, reduced patients' waiting time, and decreased the workload of embryologists.
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Eligibility Criteria
Inclusion Criteria:
* Women aged from 18
* Undergoing no more than 3 previous IVF/ICSI cycles
* Had at least a single good-quality blastocyst frozen.
* Endometrium preparation using artificial cycle
* Agree to single blastocyst transfer
* Not participating in any interventional studies at the same …
Inclusion Criteria:
* Women aged from 18
* Undergoing no more than 3 previous IVF/ICSI cycles
* Had at least a single good-quality blastocyst frozen.
* Endometrium preparation using artificial cycle
* Agree to single blastocyst transfer
* Not participating in any interventional studies at the same time
Exclusion Criteria:
* Embryos from cycles after in-vitro maturation, pre-implantation genetic testing (PGT)
* Having contraindications for exogenous hormone administration (e.g., breast cancer, thromboembolic disease)
* Having uterine abnormalities (e.g., adenomyosis, intrauterine adhesions, unicornuate/ bicornuate/ arcuate uterus; unremoved hydrosalpinx or endometrial polyp)
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