Evaluating the Utility of Implementing Microfluids for Sperm Preparation Compared to Conventional Method of Density Gradient Centrifugation in a PGT-A Program: a Sibling Oocyte Study
Recruiting
N/A
Interventional Study
Semen Analysis
ICSI
PGT-A
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
At a Glance
- Sex
- Any
- Study type
- Interventional
- Purpose
- Basic Science
- Participants needed
- 100 (estimated)
- Sponsor
- ART Fertility Clinics LLC · Other
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About This Trial
In assisted reproductive technology (ART), sperm preparation aims to select the most viable sperm for ICSI. Unlike conventional methods like density gradients or sperm washing, microfluidic techniques mimic natural selection in the female reproductive tract by using laminar flow without centrifugation, reducing the risk of DNA damage. This method isolates highly motile sperm while filtering out de…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
1. Women with at least 8 MII per cycle after denudation (AFC≥8).
2. Women of all ages.
3. All embryo qualities ≥BL3CC at the time of biopsy on day 5, 6 and/or 7.
4. Fresh sperm used from ejaculate with a concentration ≥1 mill/ml and ≥10% motility (A+B).
5. Sperm samples with a m…
Contacts