Studying the Effects of Nicotine Concentration and Flavor on Alcohol Use in Young Adults
Recruiting
N/AInterventional Study
Alcohol-Related Carcinoma
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
Ready to participate?
Review the details below, then apply to join this clinical trial.
At a Glance
Age
21 – 30
Sex
Any
Study type
Interventional
Purpose
Prevention
Participants needed
20 (estimated)
Sponsor
Ohio State University Comprehensive Cancer Center · Other
Who this trial is looking for
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This clinical trial studies the use of both (co-use) oral nicotine pouches (ONPs) and alcohol among young adults and whether ONP nicotine concentration and flavor affect alcohol use. The co-use of nicotine and alcohol has grown among young adults and the increase in ONP use among young adults may be a contributing factor. ONPs do not contain tobacco leaf and may reduce cancer risk for those who sw…
This clinical trial studies the use of both (co-use) oral nicotine pouches (ONPs) and alcohol among young adults and whether ONP nicotine concentration and flavor affect alcohol use. The co-use of nicotine and alcohol has grown among young adults and the increase in ONP use among young adults may be a contributing factor. ONPs do not contain tobacco leaf and may reduce cancer risk for those who switch from traditional tobacco products (e.g., cigarettes, moist snuff) to ONPs. However, given that alcohol is a cancer-causing agent, using ONPs might increase alcohol use among young adults, which may cause an increase in their risk of cancer. ONPs come in different nicotine concentrations and flavors, with young adults expressing a preference in nicotine concentration or flavor for use while drinking. The different nicotine concentrations and flavors could lead users to drink more or longer. Studying the co-use of ONPs and alcohol among young adults may help researchers understand whether ONP nicotine concentrations and flavors affect alcohol use. This information may be used to help guide future ONP regulations and cancer prevention interventions targeted to young adults.
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* 21-30 years old
* Use ONPs daily
* Drink alcohol at least three days/week
* Read and speak English
* Own an iPhone (required for BACtrack Skyn wristband)
* Used 6 mg nicotine concentration ONPs on at least 20 days of past month
Exclusion Criteria:
* Use of other tobacco prod…
Inclusion Criteria:
* 21-30 years old
* Use ONPs daily
* Drink alcohol at least three days/week
* Read and speak English
* Own an iPhone (required for BACtrack Skyn wristband)
* Used 6 mg nicotine concentration ONPs on at least 20 days of past month
Exclusion Criteria:
* Use of other tobacco products \> 10 days/month
* Unstable or significant medical condition
* Unstable or significant psychiatric conditions (past and stable conditions will be allowed)
* History of cardiac event or distress within the past three months
* Currently pregnant, planning to become pregnant within six months, or breastfeeding (all participants assigned female at birth will take a pregnancy test at each clinic visit before provision of study products; a negative test will be needed to proceed with product sampling)
Contacts
The Ohio State University Comprehensive Cancer Center
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