Efficacy and Safety of Adapalene Gel and Hyaluronic Acid Versus Adapalene Gel Alone in Mild to Moderate Acne Vulgaris

Recruiting Phase 4 Interventional Study
Acne Vulgaris
No Placebo Group Every participant receives an active treatment — no one gets a placebo. Prior Safety Data This treatment has already been tested in at least one earlier human trial.
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At a Glance
Sex
Any
Trial phase
Phase 4
Study type
Interventional
Purpose
Treatment
Participants needed
120 (estimated)
Sponsor
Badr University · Other
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About This Trial
Acne vulgaris affects around 85% of adolescents and young adults. Adapalene, a topical retinoid, is a common treatment but often causes irritation, leading to poor adherence. Hyaluronic acid (HA), known for its hydrating and anti-inflammatory properties, may help reduce these side effects. This prospective, open-label, randomized controlled trial compares adapalene 0.1% gel combined with HA serum…
Trial Locations
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Eligibility Criteria
Inclusion Criteria: * Patients with mild to moderate acne vulgaris who have not used topical retinoids or systemic acne treatments within the past 3 months will be included. Exclusion Criteria: * patients with severe acne, nodulocystic acne, secondary infections, known hypersensitivity to adapale…
Contacts

Hebatallah Moustafa, PhD

01001652500

hebatallah.ahmed@buc.edu.eg

CONTACT