No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
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At a Glance
Age
18 and older
Sex
Any
Study type
Interventional
Purpose
Treatment
Participants needed
30 (estimated)
Sponsor
Georgetown University · Other
Who this trial is looking for
This trial is looking for adults with vision loss due to specific brain damage. Participants will receive training and a special type of stimulation to see if it helps improve their vision.
Are You a Good Fit for This Trial?
Rules you outSevere mental health challengesSevere CNS diseasesOcular disease
You may be able to join if
I am at least 18 years old.
I can give informed consent and follow study procedures.
I have brain damage that causes vision loss.
I am at least three months post-stroke or brain injury, or have a stable brain tumor.
You may not be able to join if
I have severe brain diseases not related to my vision loss.
I have serious mental health issues that could affect the study.
I have vision loss from an eye disease.
I have had a head injury in the past.
Summarized in plain language from this trial's official eligibility criteria.
The full criteria are further down this page — only the research team can
confirm whether you qualify.
Think this trial could be right for you?
Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.
The VIBRANT (Vision Improvement through Behavioral Rehabilitation And Neuroplasticity Training) study is a prospective, double-blind, crossover design (within-subject) in participants with homonymous hemianopia-a type of visual field loss resulting from damage to the post-chiasmatic visual pathways. It aims to investigate whether transcranial random noise stimulation (tRNS) combined with perceptua…
The VIBRANT (Vision Improvement through Behavioral Rehabilitation And Neuroplasticity Training) study is a prospective, double-blind, crossover design (within-subject) in participants with homonymous hemianopia-a type of visual field loss resulting from damage to the post-chiasmatic visual pathways. It aims to investigate whether transcranial random noise stimulation (tRNS) combined with perceptual learning-based training has potential for improving visual impairments.
Trial Locations
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Status
Eligibility Criteria
A. Stroke, brain tumor, or traumatic brain injury patients
Inclusion Criteria:
1. At least 18 years of age.
2. Capable of providing informed consent and complying with study procedures.
3. Unilateral or bilateral focal brain damage causing loss of vision.
4. At least three months post-stroke or tr…
A. Stroke, brain tumor, or traumatic brain injury patients
Inclusion Criteria:
1. At least 18 years of age.
2. Capable of providing informed consent and complying with study procedures.
3. Unilateral or bilateral focal brain damage causing loss of vision.
4. At least three months post-stroke or traumatic brain injury, or a stable brain tumor within the past year.
Exclusion Criteria:
1. Severe CNS diseases or disorders unrelated to the focal lesion, which could interfere with study results.
2. Severe mental health challenges that could interfere with study results, or current or recent (within the past 6 months) drug or alcohol abuse or addiction as defined by DSM-5.
3. Vision loss resulting from ocular disease or disorder.
B. Healthy volunteers (age-matched controls):
Inclusion Criteria:
1. At least 18 years of age.
2. Capable of providing informed consent and complying with study procedures.
Exclusion Criteria:
1. Any CNS diseases or psychiatric disorders (e.g., epilepsy, schizophrenia) that would interfere with study results.
2. Previous head injury.
3. Present or past (within past 6 months) drug or alcohol abuse or addiction based on DSM-5.
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