Home-Based Light Therapy for Major Depressive Disorder
Feasibility of Home-Based Intermittent 60Hz Light Therapy for Major Depressive Disorder (MDD)
Recruiting
N/A
Interventional Study
Depression
MDD
Major Depressive Disorder
Major Depressive Episode
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
At a Glance
- Age
- 24 – 65
- Sex
- Any
- Study type
- Interventional
- Purpose
- Treatment
- Participants needed
- 40 (estimated)
- Sponsor
- NYU Langone Health · Other
Who this trial is looking for
This trial is looking for adults with major depression. Participants will use a special light therapy device at home for 30 minutes daily for three weeks. They will also have remote check-ins to discuss their symptoms.
Are You a Good Fit for This Trial?
You may be able to join if
- I am between 24 and 65 years old.
- I have been diagnosed with Major Depressive Disorder.
- I scored 17 or higher on the Hamilton Depression Rating Scale.
- I have been on the same antidepressant medication for at least 30 days.
- I can provide informed consent and follow study procedures.
- I have a quiet space at home for light therapy.
- I speak English.
You may not be able to join if
- I have a primary neurological or autoimmune disorder.
- I have other serious mental health conditions.
- I have had an alcohol or substance use disorder recently.
- I have a history of bipolar disorder or psychosis.
- I have serious thoughts of harming myself.
- I have a history of seizures or epilepsy.
- I experience migraines or sensitivity to light.
- I am currently pregnant, planning to become pregnant, or breastfeeding.
Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.
Think this trial could be right for you?
Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.
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About This Trial
This pilot study evaluates the feasibility, safety, and preliminary efficacy of home-based 60Hz intermittent light therapy in adults with a major depressive episode (MDE). Participants will be randomized in a 2:1 ratio to receive either active or sham 60Hz intermittent light stimulation for 30 minutes daily (Monday through Friday) over three weeks. The light is delivered through a wearable headset…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Age between 24 and 65 years (inclusive)\*.
* Confirmed diagnosis of Major Depressive Disorder (MDD), based on MINI interview.
* Hamilton Depression Rating Scale (HDRS-17) score ≥17 at screening.
* On a stable dose of antidepressant medication for at least 30 days prior to HDRS…
Contacts